Stem cell therapies in preclinical models of stroke. Is the aged brain microenvironment refractory to cell therapy?

Attractive therapeutic strategies to enhance post-stroke recovery of aged brains include methods of cellular therapy that can enhance the endogenous restorative mechanisms of the injured brain. The translational failure of experimental therapies in post-stroke aged subjects might at least partially be related to the aged brain microenvironment. However, we have shown that G-CSF alone is effective in improving behavioral recovery after stroke in aged rats. In subsequent experiments we tested the hypothesis that treating post-stroke aged rats with the combination of bone marrow-derived mononuclear cells (BM MNC) or bone marrow-derived mesenchymal cells BM MSC and G-CSF might improve the long term (56 days) functional outcome.
To know more@ or


  1. Get the perfect stroke treatment in Punjab only at the Mind Plus Retreat. Here people can get the best ever solution for their any type of the stroke problem with 100% successful results.


Post a Comment

Popular posts from this blog

Have your glance at the program-Brain disorders 2018

Scientific program for Brain Disorders 2018

High Lights of Brain Disorders 2018