RARE CASE OF INFLAMMATORY PSEUDOTUMOUR OF CENTRAL NERVOUS SYSTEM
Inflammatory Pseudotumours(IPT) are mostly benign
lesions , mimicking malignant lesions and affecting almost all organ systems
and are characterised by fibrotic ground tissue and polyclonal mononuclear
infiltrate on histopathology. It is a disease of unknown pathogenesis and the
brain is a rare site of occurrence. Here we present one such case we operated
recently in our department.
Inflammatory Pseudotumour(IPT) is a rare
nonneoplastic condition that usually involves the lung and orbit, but is known
to affect almost all the organ systems. The term ´Inflammatory Pseudotumour´ was
coined by Umiker and Iverson in 1954, after finding out that the clinical and
image findings mimicked that of a malignant lesion. The cause of IPT is
unknown. It is characterised histologically by the presence of acute and
chronic inflammatory cells with a variable fibrotic response. It is also called spindle cell Pseudotumor, plasma
cell granuloma, inflammatory myofibroblastic tumor. The condition is rare in
the brain and is usually an intracranial extension of an extracranial tumour
arising from the orbit. Rarely , the condition is primarily intracranial or
within spinal cord, affecting young men mostly.
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